Clinical Features And Outcome Of Bacterial Meningitis In The Elderly

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University of Louisville Journal of Respiratory Infections

The main demographic, comorbidities, clinical findings, radiographic, laboratory, severity and outcome features of patients are showed in Table 1A and Table1B. Table 1A Main characteristics of study population. Differences between survivors and mortalities by univariate analysis. Table 1B Patient characteristics of study population. Differences

Listeriosis in Adults: A Changing Pattern. Report of Eight

pressive therapy, clinical presentation, antimicro-bial therapy, and outcome. Cases of listeriosis re-ported in insufficient detail for critical analysis were excluded from this review. For the purposes of this review, diagnoses were defined as follows. Meningitis was accepted as the diagnosis if L. monocytogenes was isolated from

11 Microbial fact sheets - WHO

11.1 Bacterial pathogens Most bacterial pathogens potentially transmitted by water infect the gastrointes-tinal tract and are excreted in the faeces of infected humans and animals. However, there are also some waterborne bacterial pathogens, such as Legionella, Burkholderia pseudomallei and atypical mycobacteria, that can grow in water and soil


Clinical Features Typical patient is an elderly nursing home resident bacterial meningitis, insulin does not result in better clinical outcome

Original Articles Spectrum of Complications and Mortality of

Bacterial meningitis is more common in the very young and the elderly. In the present series. more elderly patients were affected by acute bacterial menitt-itis. In bacterial meningitis there is a slight male predominance. Men outnumbered women by a ratio of 6:5 in a German study of bacterial meningitis in adults. 1 3 However, one

Journal of Neurology,Neurosurgery,andPsychiatry December Vol

elderly PAULJ ESLINGER,HANNADAMASIO,NEILLGRAFF-RADFORD,ANTONIORDAMASIOpage 1319 Clinical Features Late outcome ofvery severe blunt head trauma:

Neisseria meningitidis : A Neglected Cause of Infectious

bacterial meningitis (G00.9, ISCD-10) with a case fatality rate of 73%, over a 5-year period; a petechial rash was present in three and arthritis in one, suggesting a possible diagnosis of meningococcal meningitis. Of these cases, 73% were younger than five years old and eight were from rural communities, but none were from the patient s village.

Tuberculosis Meningitis - Challenges and Opportunities : C Meyer

9. Schutte CM. Clinical, Cerebrospinal Fluid and Pathological Findings and Outcomes in HIV-positive and HIV-negative patients with Tuberculous Meningitis. Infection 2001; 29: 213-217 10.Thwaites GE. Diagnosis of adult tuberculous meningitis by use of clinical and laboratory features. Lancet 2002; 360: 1287-1292 11.Schoeman JF.

ORIGINAL ARTICLE Increasing Prevalence of Multidrug-Resistant

In the United States, Streptococcus pneumoniae is the most commonly identified bacterial cause of meningitis, otitis media, and community-acquired pneumonia, and it is a frequent cause of bacteremia. In the past, approximately 80 percent of patients hospitalized with bacteremic pneumococcal infections died of their illness.

Characterization of a Listeria monocytogenes meningitis mouse

infection is food, and it primarily affects elderly and im-munocompromised persons, [7] in whom it can cause up to 40% of community-acquired bacterial meningitis cases [8, 9]. A nation-wide prospective cohort study on L. monocytogenes meningitis described an increasing mortal-ity rate over time, from 17 to 36% over the past decade [10].

A Case of Bacterial Meningitis Due to Vancomycin Resistant

resistant E. casseliflavus meningitis in a 17-months-old girl who has been successfully treated with linezolid. The patient completely recovered after fourteen days of linezolid treatment. Vancomycin-resistant E. casseliflavus may be a potential pathogenic cause of meningitis in children with good

COVID 19 -

21 Patients admitted to the ICU. Mean age 70. Comorbidities 86% CKD 47%, CHF 42%, DM 33%, COPD 33%. Mean duration of symptoms 3.5d. Abnormal CXR 95%. ICU within 24h of admission 81%


meningococcal disease [16]. The first description of the clinical and pathological features of bacterial meningitis was only recorded in the early 19th century. Epidemic cerebrospinal meningitis was first described by Gaspard Vieusseux of Geneva in 1806 [17]. Vieusseux observed that many

RESEARCH ARTICLE Open Access Three-year multicenter

Background: Listeria monocytogenes is the third most frequent cause of bacterial meningitis. The aim of this study is to know the incidence and risk factors associated with development of acute community-acquired Lm meningitis in adult patients and to evaluate the clinical features, management, and outcome in this prospective case series.

Viral Encephalitis I. General Principles

Bacterial meningitis was discussed in a previous lecture. Viral meningitis is an infection of the subarachnoid space caused by a virus. The predominant clinical features of fever, headache, and nuchal rigidity (neck stiffness), are often accompanied by nausea, vomiting, and malaise. Viral meningitis is usually a self-limited illness which lasts

Community-acquired bacterial meningitis in adults in the

occurrence and outcome of bacterial meningitis (MeninGene).7 19 Here, we report data from this study, including the incidence, causative pathogens, clinical features, and prognostic factors in adults with community-acquired bacterial meningitis in the Netherlands from 2006 to 2014. Methods Study population

Capnocytophaga canimorsus blebitis: case report and review of

sent for fungal and bacterial cultures. Patient was pre-scribed a prolonged course of moxifloxacin drops; ini-tially every 1 h and eventually tapered to four times a day. Prednisolone acetate drops were added, and the pa-tient was monitored regularly in clinic with improve-ment to his clinical condition.

New Insights into Determinants of Listeria Monocytogenes

infanseptica), and meningitis in neonates. Clinical features of invasive liste-riosis derive from the unique capacity of L. monocytogenes to cross three barriers: the intestinal, blood brain, and placental barriers (Lecuit, 2005). The clinical outcome of listeriosis is influenced by the pathogenic potential of the infecting strain.

Articles Clinical features, complications, and outcome in

Clinical features, complications, and outcome in adults with pneumococcal meningitis: a prospective case series Martijn Weisfelt, Diederik van de Beek, Lodewijk Spanjaard, Johannes B Reitsma, Jan de Gans Summary Background Bacterial meningitis is a grave disease of high incidence, especially in less developed countries. Here, we

122800 Increasing Prevalence of Multidrug-Resistant

is the most commonly identified bacterial cause of meningitis, 1 otitis media, nearly 20 percent for bacteremic disease in elderly information on clinical characteristics, and disease outcome.

Viral causes of acute Clinical scenario #1 encephalitis

West Nile virus - clinical Most human infections clinically inapparent 1/5 febrile illness; 1/150 CNS involvement Elderly at increased risk for neuro sx and death Rash and lymphadenopathy common 2-15 day incubation period Neuroinvasive features (enceph > meningitis) Acute flaccid paralysis (anterior horn cells)

A Milk-Borne Outbreak of Serious Infection Due to

an elderly woman aged 80 years who had died on 13 May of meningitis and septicaemia. She died 14 h after admission to hospital but blood culture yielded a growth of haemolytic streptococcus Group C not fully identified as S. zooepidemicus. Because of the clinical and bacteriological similarities, relatives of

The diagnostic accuracy of Kernig's sign, Brudzinski's sign

bacterial meningitis carries a mortality of approximately 25% despite effective antibiotic therapy, and delays in antibiotic initiation can adversely affect clinical outcome [1-3]. Optimal evaluation of the risk of meningitis requires diagnostic assessment of a patient s clinical features.


Clinical Features The incubation period is 14 to 16 days after exposure, with a range of 10 to 21 days. The incubation period may be prolonged (e.g., up to 28 days or more) in those who have received postexposure prophylaxis with varicella specific immune globulin. Adriana Lopez, MHS; Theresa Harrington, MD, MPH&TM; and Mona Marin, MD Varicella

Differential Diagnosis of Stroke in a Setting of High HIV

fungal, bacterial, and tuberculous meningitis [TBM], cerebral toxoplasmosis, neurosyphilis, and neurocysticercosis). Most of these (but not all) are HIV related and may cause a clinical syndrome similar to stroke.6 After meningitis, rapid onset focal cerebral deficit is the second commonest disease of the central nervous system

Encephalitis in the Pediatric Population

2. Recognize the clinical features of encephalitis. 3. Be able to conduct a diagnostic investigation of a patient with encephalitis by using clinical and laboratory criteria. 4. Know the anticipated clinical course of different types of encephalitis. 5. Be familiar with the modalities used to treat encephalitis. 6.

Florida Department of Health Pasco County

STD/HIV: Clinical Timeline: printable graphic that provides key clinical facts and images to aid in the diagnosis of RMSF Tickborne Diseases of the United States Manual: manual for healthcare providers highlighting transmission, epidemiology, clinical, diagnostic, and treatment features for tickborne diseases throughout the country.

PA 739 Family Medicine Syllabus - School of Medicine and

Director of Clinical Education 1260 HSLC, 750 Highland Ave. Madison, WI 53705 608-265-6723 [email protected] Amanda Johnson, MSM, PA-C Clinical Faculty 1264 HSLC, 750 Highland Ave. Madison, WI 53705 608-263-2865 [email protected] Rosa Retrum, MSE Clinical Coordinator 1262 HSLC, 750 Highland Ave., Madison, WI 53705 608-265-6457 [email protected]

13 Meningococcal disease

13.2 Clinical features Table 13.1 below describes the symptoms and signs of meningococcal disease individuals may present with some or all of these. Meningococcal septicaemia is more common than meningitis, and presentation varies from a mild non-specific illness to rapid progression with fatal outcome.

Long-Term Prognosis for Clinical West Nile Virus Infection

aAt 12 months post -onset, baseline status for each outcome was assessed; for each outcome, patients were asked to report the deg ree to which they experienced the signs and symptoms at baseline (by recall) and at 12 months postonset. bEach outcome w as scored 0 2 according to the following scale: always = 2, sometimes = 1, never = 0

Learning from errors Pitfalls in the management of herpes

elderly.5 Recognising encephalitis in the elderly can be challenging, as they are at risk of a broader range of neuro-logical disorders including stroke.5 Early studies showed that HSVE has a mortality exceed-ing 70% if untreated, reducing to 15 25% with acyclovir treatment.2 Early treatment predicts improved outcomes,

TBM in UK PROTOCOL v17 2nd August 2010

distinguishing it from acute bacterial meningitis. Delayed diagnosis is associated with poor outcome. Untreated, it is universally fatal and lengthy treatment is often initiated on a presumptive diagnosis. There are very few UK studies on TBM3, 4 Much of our information on TBM is from research conducted in countries with a high prevalence of TB.

RESEARCH ARTICLE Open Access The spectrum of acute bacterial

clinical features, and outcome of elderly patients with acute bacterial meningitis (ABM) compared with younger adults. Methods: During 1982 2010, all patients with ABM were prospectively evaluated. There were two groups: I (15 64 years) and II (≥ 65 years). All patients underwent clinical examination on admission and at discharge

Hospital Toolkit for Adult Sepsis Surveillance

and outcome monitoring. Different definitions for sepsis are needed for different purposes, which could include clinical care, research, surveillance, and quality improvement and audit. 5,6 For example, a sepsis definition optimized for public health surveillance would prioritize reliability and validity across healthcare facilities, and

CHAPTER 1 Unconsciousness and Coma

Table 1.2 Causes of meningitis/encephalitis. Bacterial Neisseria meningitidis, Streptococcus pneumoniae, listeria (elderly), Haemophilus infl uenzae, TB Viral Herpes simplex, Coxsackie, mumps, echovirus, HIV Fungal Cryptococcus neoformans Other Drugs (trimethoprim/NSAIDs), sarcoidosis, systemic lupus erythematosus Box 1.4 Atypical clinical

Rare case of a 3-year-old with Candida skull base

as in this case. The clinical features associated with fungal SBO in adults include underlying chronic sinusitis, sinus pain, facial/ periorbital swelling and the absence of purulent ear discharge, whereas in bacterial infection otalgia and purulent discharge can be predominating features.6

Three Cases of Bacteremia Caused by Vibrio cholerae O1 in

The second twin followed a similar clinical course and died on day 2. Blood culture was negative. The mother was a healthy 21-year-old, with no diarrheal disease. We were unable to recall her for stool culture. Case 2 (Adult) A previously healthy 45-year-old woman was admitted to QECH in September 1998 with profuse, watery diarrhea.

Clinical Significance and Epidemiology of NO-1, an Unusual

ill Sutured Major clinical features Antibiotic treatment/outcome 1 MA F/22 Cat Hand 8 Unk. Cellulitis, loss of motion, purulent drainage, fever Improved with cephradine + penicillin (OP) 2 IL M/45 Dog Hand 5 Unk. Purulent drainage, redness and swelling extending up to forearm Cefadroxil (OP); next day admitted to hospital and gradual

4: Acute community-acquired meningitis and encephalitis

severity of symptoms and risk of adverse outcome, suggest-ing a role for adjunctive corticosteroids in treatment. Clinical features3,4 Symptoms of acute meningitis may be subacute and non-specific. Signs of meningeal irritation are important clues; classical descriptions highlighted the importance of per-