Comparative Pulmonary Toxicities And Carcinogenicities Of Chronically Inhaled Diesel Exhaust And Carban Black In F344 Rats

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Diesel fuel and exhaust emissions: Is there a human

3 Nikula KJ, Snipes MB, Barr EB, et al.Comparative pulmonary toxicities and carcinogenicities of chronically inhaled diesel exhaust and carbon black in F344 rats. Fund.Appl.Toxicol1995: 25: 80-94. 4 Heinrich U, Fuhst R, Rittinghausen S, et al.Chronic inhalation exposure of Wistar rats and two different strains of mice to diesel engine exhaust, carbon black, and titanium dioxide. Inhal.Toxicol1995; 7: 533-56.

Carbon Black: Kuempel et al. Respond

Mauderly JL. 1995. Comparative pulmonary toxicities and carcinogenicities of chronically inhaled diesel exhaust and carbon black in F344 rats. Fundam Appl Toxicol 25:80 94. Sager TM, Castranova V. 2009. Surface area of particle admin-istered versus mass in determining the pulmonary toxicity of ultrafine and fine carbon black: comparison to ultrafine

Pulmonary Toxicity of Inhaled Diesel Exhaust and Carbon

Dr. Mauderly and coworkers exposed F344/N rats to clean air or to one of two levels (2.5 or 6.5 mg of particles/m3 of diesel exhaust or air) of either emissions from a light-duty diesel engine or carbon black particles. The exposures lasted for 16 hours/day, 5 days/week, for 24 months. The carbon black particles were similar to the soot particles