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MicroRNAs and Lung Cancer: A Review Focused on Targeted Genes
disease-free and survival rates of lung cancer remain quite low. MicroRNAs are small, non-coding RNAs that con-sist of an average of 22 nucleotide molecules. MicroRNAs play an important role in the development, progression, metastasis, diagnosis and prognosis of lung cancer. This review summarizes the recent publications abnormally
Review Article - researchgate.net
Translational lung cancer research, Vol 4, No 2 April 2015 157 Translational lung cancer research. All rights resered. www.tlcr.org Transl Lung Cancer Res 2015;4(2):156-164 The RET fusion in LADC
Quality of life, pain, and functional respiratory recovery
cell lung cancer: a review of the literature comparing minimal invasive and open procedures Goussens Alexandre, Lacroix Valérie Department of cardiovascular and thoracic surgery, Cliniques Universitaires Saint Luc, Brussels 1200, Belgium.
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Population and Development Review a Journal of the Population
Cite this article as: Samuel H. Preston and Irma T. Elo, Anatomy of a Municipal Triumph: New York City s Upsurge in Life Expectancy, Population and Development Review, accepted article preview 16 December 2013; doi: 10.1111/j.1728-4457.2013.00648.x. This is a PDF file of an unedited peer-reviewed manuscript that has been accepted
291 Review Article The microbiome and lung cancer
putative role of microbiome in lung cancer is discussed with a brief discussion on the methods for isolation of Review Article The microbiome and lung cancer Abhiram Maddi1, Amarpreet Sabharwal 1, Timothy Violante, Sunita Manuballa2, Robert Genco, Santosh Patnaik 3, Sai Yendamuri
Efficacy of pemetrexed-based regimens in advanced non small
Lung cancer is the leading cause of cancer-related mortality worldwide for both men and women.1,2 Non small cell lung cancer (NSCLC) is the most common subtype, accounting for approximately 80% 85% of all lung cancers.1,2 Most patients with NSCLC are diagnosed at advanced stages (IIIb and IV) of the disease, with only
Management of lung cancer in the COVID-19 pandemic: a review
metastatic cancer, haematological neoplasms, or lung cancer showed a worse evolution. Similar results were obtained in the study carried out by Jee et al., in patients under active chemotherapy treatment, wherein its diagnosis of lung neoplasia was determined as a predictor of poor prognosis in COVID-19 infection,
6239 Review Article on Small Cell Lung Cancer Radiosurgery
Herein we will review the emerging data for first-line SRS in the management of SCLC brain metastases and the potential for its increasing role in the setting of a greater utilization of MRI surveillance and improving systemic therapies. Keywords: Stereotactic radiosurgery (SRS); whole brain radiation therapy (WBRT); small-cell lung cancer
Screening for Lung Cancer - CHEST Home
for lung cancer from a clinical risk prediction calculator who are healthy enough to beneﬁt from lung cancer screening, and that low-dose CT screening could be considered in these individuals. Remark: A risk threshold of 1.51% over 6 years on the PLCOm2012 calculator is an example of high risk. Remark: In the United States, health insurance
Challenges in lung cancer screening: a review of implemented
cancer screening modalities (8,9). The number needed to screen with LDCT to prevent one death from lung cancer is 320 (10). For comparison, the number needed to screen to prevent one death from breast or colon cancer is 1,904 Review Article Challenges in lung cancer screening: a review of implemented programs
5953 Review Article on Oligometastasis- Fallacy or Real Deal
Non-small cell lung cancer (NSCLC) is the leading cause of cancer associated mortality in the United States despite targeted screening of at-risk populations (1,2). Most patients will present with advanced or metastatic disease; moreover, a large proportion of those with advanced disease will later
Environmental and Occupational Causes of Cancer
Causes of Cancer A Review of Recent Scientifi c Literature Richard Clapp, D.Sc. Genevieve Howe, MPH Molly Jacobs Lefevre, MPH Prepared by Boston University School of Public Health and the Environmental Health Initiative, University of Massachusetts Lowell For the Cancer Working Group of the Collaborative on Health and the Environment September 2005
Managing Massive Hemoptysis
to surgical lung biopsy in the diagnosis of diffuse parenchymal lung disease.30,31 However, because of the elevated risk of major hemorrhage, expert consensus suggests routine use of a bronchial blocker or Fogarty balloon to isolate procedural bleeding in patients who are intubated.30 In addition, some protocols recommend
A Pictorial Review of Changes in the BI-RADS Fifth Edition
head injury (HI-RADS), lung cancer screening (lung-RADS), and prostate cancer (PI-RADS) lexicons. Overview of BI-RADS Fifth Edition: Mammography Revisions The mammography lexicon has changed from the previous edition by eliminating and/or con-solidating terminology, with a few new addi-tions. The complete list of changes is described in Figure 1.
Breast Cancer: A Review of the Literature
Women treated for breast cancer have about a 1% greater chance per year of devel-oping a new second cancer in either the treat-ed breast or the other breast. Therefore, pre-vious breast cancer is an accepted risk factor for development of breast cancer. 23 Ten per-cent of women with breast cancer develop a second breast cancer, and women with
Advances in Radiation Oncology - ASTRO
Extent of prior lung irradiation and mortality in COVID-19 patients with a cancer history Manuscript Draft Manuscript Number: ADVANCESRADONC-D-20-00162 Article Type: Scientific Article Section/Category: COVID-19 Corresponding Author: Nitin Ohri, M.D. Albert Einstein College of Medicine and Montefiore Medical Center New York, NY UNITED STATES
1709 Review Article on Lung Cancer Multidisciplinary Care
as non-small cell lung cancer in more than 80% of cases and small cell lung cancer in about 15% of cases (3). Lung cancer is associated with significant morbidity, with the most distressing symptoms commonly reported by people including breathlessness, pain, fatigue, and anorexia (4,5). Symptoms experienced by people with lung cancer
6 Review Article Page 1 of 6 Management of empyema: a
who had surgery for lung cancer were reported (42). The incidence of empyema after lung cancer surgery was 0.9% and mortality was 11.6% (42). The frequency of empyema was around 10% before 2000, but around 1% after 2000 (43-49). Mortality was 14.8% or 22.2% around 1980, but it has been decreasing due to medical progress (42,44,50). Discussion
February 22, 2011, neoplasia 1 lecture
CANCER Metastasis = Malignant. Metastasis: spread to distant, non-contiguous site Lymphatic metastases (nodes) Hematogenous metastases (lung, liver, bone, brain) Implantation in body cavities Fatal if untreated. If the tumor gains access to body cavities (pleural space, etc ) it can implant in these cavities
1666 Original Article Significance of risk factor analysis
Lung cancer is the leading cause of death for cancer worldwide, with non-small cell lung cancer (NSCLC) accounting for about 85% of all lung cancers reported in relevant literature (1,2). Mediastinal lymphatic metastasis is the main diffusion pathways for lung cancer, and also one of the important factors influencing the prognosis of lung
A narrative review of the role of endoscopic ultrasound (EUS
Objectives: endosonography role in lung cancer staging Lung cancer is one of the most common solid malignant disease, with non-small-cell lung cancer (NSCLC) being its most common variant. Accurate staging is required for planning the most appropriate treatment (1,2). Surgery or local radiotherapy are the elective treatment for localized disease.
1653 Review Article on Lung Cancer Multidisciplinary Care A
A retrospective review of lung cancer patients at a single institution also found discussion at an MDM had no impact on survival for patients with lung cancer [odds
Introduction to Cancer Biology - University of Georgia
been linked to liver and mouth/throat cancers in both males and females. Breast cancer risk is high in females who drink to excess. Smoking and tobacco use significantly increases the risk of lung cancers equally in males and females, and there is also a slightly higher risk of mouth/throat cancers. Source: SEER Cancer Statistics Review, NCI, USA.
Lung Cancer Causes, Risk Factors, and Prevention
The risk of lung cancer for smokers is many times higher than for non-smokers. The longer you smoke and the more packs a day you smoke, the greater your risk. Cigar smoking2 and pipe smoking are almost as likely to cause lung cancer as cigarette smoking. Smoking low-tar or light cigarettes increases lung cancer risk as much as regular
Cancer Research - Elsevier
cancer research current trends & future directions 6 Map of countries leading in cancer research output along with publication output, publication growth, and field-weighted citation impact (FWCI). World average (indicated by dashed circles) for publication growth: 9.93% / World average for field-weighted citation impact: 1.00.
OPEN ACCESS EC PULMONOLOGY AND RESPIRATORY MEDICINE Review
cancer, 5 patients with the kidney cancer, 11 with brain metastatic tumors, 18 patients with the breast cancer tumors, 5 patients with the lung cancer and 5 patients with colorectal cancer. Table 1 The methodology of this study was based on 5 days of water fasting to make the normal cells go to the catabolism state, after 5 days
Review Role of tumor microenvironment in - Journal of Cancer
prognosis in several types of cancer, including breast and prostate cancer and laryngeal carcinoma -49]. [46 Chemokine (C X C motif) ligand 12 (CXCL12), violently uttered in CAFs, may induce epithelial-mesenchymal transition (EMT) of cancer cells to promote cancer progress in gastric and prostate cancers [50, 51]. Moreover, one team
8 Review Article Page 1 of 8 Non-intubated thoracic surgery
47. Lin R, Che G. Risk factors of cough in non-small cell lung cancer patients after video-assisted thoracoscopic surgery. J Thorac Dis 2018;10:5368-75. 48. Xie MR, Zhu YF, Zhou MQ, et al. Analysis of factors related to chronic cough after lung cancer surgery. Thorac Cancer 2019;10:898-903. 49. Pan LY, Peng LP, Xu C, et al. Predictive factors
11 Review Article Venous thromboembolism in patients with
IIIB, IIIC, and IV lung cancer whose Eastern Cooperative Oncology Group (ECOG) performance status score is in the range of 2 to 4 due to causes related to the lung cancer itself or complications of anti-tumor drugs, at the same time these patients have a high probability of benefiting Review Article
An improved method to build lung cancer PDX models by
patients who were diagnosed with lung cancer or were suspicious for lung cancer. All the specimens were cut directly from the surgery performed by the First Affiliated Hospital of Soochow University, and the diagnosis was certified on fast icy cross-section during the operation. Establishment of patient-derived tumor xenografts in
The Future of Cancer Research: Accelerating Scientific Innovation
vision for cancer research, progress toward the goal of preventing, controlling, and curing cancer will continue to proceed incrementally instead of accelerating to meet the needs of the American people.
6 Review Article Page 1 of 6 Surgery for recurrent thymoma
in cancer care and cardiovascular disease (5). For example, in the case of lung cancer, there was a 40% reduction in the number of patients referred for urgent review for the investigation of possible lung cancer (6). This is likely to be driven by the seemingly appropriate advice to stay at home and isolate if one has symptoms of COVID-19 such
in a Randomized Trial - NEJM
Jan 29, 2020 from lung cancer at 10 years was 0.76 (95% confidence interval [CI], 0.61 to 0.94; P = 0.01) in the screening group as compared with the control group, similar to the values at years 8 and 9.
Review Cancer and Radiation Therapy: Current Advances and
countries; 63% of cancer deaths are reported to be from developing countries [1, 2, 3]. Cancer is a mul-tigenic and multicellular disease that can arise from all cell types and organs with a multi-factorial etiolo-gy. Hanahan and Weinberg  have identified six cancer cell phenotypes or hallmarks of cancer: cells
Lung Cancer: Diagnosis, Treatment Principles, and Screening
Feb 15, 2015 Lung cancer is classified histologically into small cell and non small cell lung cancers. The most common symptoms of lung cancer are cough, dyspnea, hemoptysis, and systemic symptoms such as
Life After Cancer Treatment
A Note About Cancer Survivors There are millions of people in the U.S. today who are cancer survivors. Three out of every four American families will have at least one family member diagnosed with cancer. To help support survivors unique needs, the National Cancer Institute (NCI) formed the Office of Cancer Survivorship (OCS) in 1996.
Understanding Lung Cancer
Q: What is lung cancer? A: Lung cancer begins when abnormal cells grow and multiply in an uncontrolled way in one or both of the lungs. Cancer that starts in the lungs is known as primary lung cancer. It can spread to other parts of the body such as the lymph nodes, brain, adrenal glands, liver and bones.
6 Original Article Page 1 of 6 The use of stereotactic body
Background: Pulmonary carcinoid (PC) tumors are rare neoplasms that account for 1 2% of lung cancer. Although surgical resection is standard treatment for PCs, not all patients are surgical candidates.
The eighth edition TNM stage classification for lung cancer
of early non small cell lung cancer and are critical for the thoracic surgical oncologist to embrace in daily practice. NewentitiessuchasT1mi,T1c,M1c,andstageIA1tumors, among others, will become regular in the language that we use to care for patients with lung cancer, and this staging framework is critical for advancing the ﬁeld of thoracic