Saliva Iodine Concentration In Children And Its Association With Iodine Status And Thyroid Function
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AMERICAN THYROID ASSOCIATION www.thyroid.org Iodine Deficiency
of iodine deficiency are related to its effect on the thyroid: GOITER Without adequate iodine, the thyroid progressively enlarges (develops a goiter) as it tries to keep up with demand for thyroid hormone production. Worldwide, iodine deficiency is the most common cause of thyroid enlargement and goiter (see goiter brochure).
iMedPub Journals Medical & Clinical Reviews 2016
interfere with thyroid gland function causing TSH elevation and lessen T3/T4 hormones in some populations which may be due to its antagonistic properties towards iodine. As an endocrine disruptor, F-induces more toxic outcome in diabetic patients. Chronic F-exposure through drinking water may leads to insulin
Primary congenital hypothyroidism: defects in iodine pathways
of thyroid hormone and the recycling of iodine, defects may occur (Table 2). Figure 1 (A) Section of a normal thyroid gland stained with haematoxylin-eosin and immuno-stained with anti-thyroglobulin. (B) Schematic drawing of a thyroid cell with the main iodination pathways. Modiﬁed from Van de Graaf et al. (24). IGF-1, insulin-like
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STEN - BMJ
bility that the thyroid function determined the production rate of the secretory component which joins 2IgAmolecules together andprevents proteo-lytic degradation of the dimers. The data given in Table 1 also seem to preclude the possibility of abnormal J-chain production in hypothyroidism. The plasma concentration of the joining chain is normal.