Acute Hypoxia Increases Intracellular L‐arginine Content In Cultured Porcine Pulmonary Artery Endothelial Cells

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Chronic hypoxia increases the NO contribution of

of chronic hypoxia (HPX) on vasodilation of the fetal heart, we exposed pregnant guinea pigs to room air or 12% O 2 for 4, 7, or 10 days. We excised hearts from anesthetized fetuses (60 6 3 days; 65-day gestation 5 term) and measured changes in both the coronary artery pressure of the isolated constant-flow preparation and endothelial nitric