Pharmacokinetics Of Antimicrobial Agents In Anuric Patients During Continuous Venovenous Haemofiltration

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Identification of Optimal Ceftazidime Dosing Regimens in

Antimicrob Agents Chemother. 1993 Mar;37(3):464-73. 9. Joos B, et al. Pharmacokinetics of antimicrobial agents in anuric patients during continuous venovenous haemofiltration. Nephrol Dial Transplant. 1996 Aug;11(8):1582-5. 10. Moriyama B, et al. Continuous-infusion beta-lactam antibiotics during continuous venovenous

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In general, in haemodynamically unstable ICU patients with oliguric/anuric acute kidney injury, continuous venovenous haemofiltration (CVVH) is the preferred method of renal replacement therapy. 5 Due to its low molecular weight, low protein binding and low V d, cefuroxime has a high removal rate; therefore, it is