Analytical Model Of Chemical Phase And Formation Of DSB In Chromosomes By Ionizing Radiation
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Podklady pro habilitační řízení-kvalitativni hodnocení
Barilla J., Lokajíček M., Pisakova H., Simr P., 2013. Analytical model of chemical phase and formation of DSB in chromosomes by ionizing radiation. Australasian Physical & Engineering Sciences in Medicine. 36, 11‐17 ISSN 0158‐9938. DOI: 10.1007/s13246‐012‐0179‐4.
INFLUENCE OF N O AND ETHANOL ON THE CHEMICAL STAGE OF
a) The proposed simulation model makes it possible to take into account all chemical reactions running during cluster diffusion. b) The model will enable us to study the influence of LET value of ionizing radiation on DNA damage to a greater detail and to better understand the influence of chemical stage. c) It will be possible to study the
Nov 04, 2020 the case of low-LET radiation the direct e ect may be practically neglected and the radical clusters meet a DNA molecule always some time after their formation. The corresponding damage e ect (formation of DSB) depends then on the evolution running in individual clusters, being in uenced by present chemical agents. Two main parallel processes in
Mutation Research/Genetic Toxicology and Environmental
domains, distributed DSB for low-LET radiation ran-domly, and described the DSB interaction probability by an inverse power law. A similar spherical domain model of chromatin struc-ture was employed by Eidelman et al. . In their approach, CA formation required a contact of two DSB-containing domains, assessed