Passage In Monolayer Influences The Response Of Chondrocytes To Dynamic Compression

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ENGINEERING OF CARTILAGE USING ADIPOSE DERIVED

apply dynamic deformational loading to ASC seeded constructs. Dynamic loading significantly inhibited ASC metabolism and downregulated cartilageā€specific ECM genes. However, 21 days of dynamic loading induced the production of type II collagen, a principal component of articular cartilage.