Mesodermal Tumors Associated With Hypoglycemia

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Cancer-Associated PIK3CA Mutations in Overgrowth Disorders

Cancer-associated activating PIK3CA mutations, when occurring in isolation during early development, cause a spectrum of rare disorders character-ized by asymmetric, and often severe, tissue growth and malformations. Tissues are not uniformly affected, surprisingly, no excess of PIK3CA-associated adult cancers has been described. Evidence

THE AMERICAN ASSOCIATION FOR THORACIC SURGERY 1961-1962

chiefly large extrapulmonary growths of certain mesodermal types The tumor may be present for some years before the metabolic disturbances become manifest. If treatme nt is unduly delayed, chronic hypoglycemia may result in brain damage. With surgical excision of these tumors a return of the blood sugar to normal levels can usually be anticipated.

Edinburgh Research Explorer

Cancer-associated activating PIK3CA mutations, when occurring in isolation during early development, cause a spectrum of rare disorders character-ized by asymmetric, and often severe, tissue growth and malformations. Tissues are not uniformly affected, surprisingly, no excess of PIK3CA-associated adult cancers has been described. Evidence

Doege-potter syndrome: a report of a histologically benign

Solitary fibrous tumors of the pleura (SFTPs) are rare neoplasms that originate from the visceral pleura. If hypoglycemia is associated with a solitary fibrous tumor, it is referred to as the Doege-Potter syndrome [1]. Occasionally, histologically benign tumors can clinic-ally present as malignant tumors [2, 3]. We describe an

Case Report: Retroperitoneal synovial sarcoma presenting as

mesodermal structures exclusively of bony, renal, visceral, adrenal, and pancreatic tissues. 4 The potential origin of retroperitoneal synovial sarcoma is primitive pluripotent mesenchyme. Histopathologically there are two types of synovial sarcomas: biphasic and monophasic. Biphasic type is an admixture of epithelial cells and spindle cells.

Primary diaphragmatic haemangiopericytoma

hemangiopericytoma associated with hypoglycemia and masculinization. Delaware State Medical Journal, 31, 29. Majno,G.andPalade, G.E. (1961). Studiesoninflamma-tion. I. The effect of histamine and serotonin on vascular permeability: an electron microscopic study. Journal of Biophysical and Biochemical Cytology, 11, 571.

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syndrome of spontaneous hypoglycemia associated with tumors of mesodermal origin was clearly recognized 2 since that time 39 new cases have been described 3 the location of the tumors has been almost equally''Endocrine System Anatomy Britannica Com May 5th, 2018 - Endocrine System Endocrine System Any Of The Systems Found In Animals For The

Tumor hypoglycemia

The syndrome of hypoglycemia associated with neoplasia is now a well- documented entity. At least 50% of the lesions have been hepatomas or fibro- sarcomas and approximately 53% of them have been found in the retroperi- toneal region or the liver. The outstanding feature of the tumors is their large size and weight.

Metastatic secondary fibrosarcoma of bone responsive to

tumours of mesodermal or epithelial origin.6 Such mechanism of hypoglycemia associated with non- Bone Tumors: Diagnosis, Treatment and Prognosis.2nd

Vascular Endothelial Growth Factor as a Target for Anticancer

continues, albeit at a much reduced level, and is associated primarily with maintenance of the vasculature, and with wound healing and menstrual cycling [3, 5-8]. Angiogenesis is essential for the growth of most primary tumors and their subsequent metastasis (Fig. 1). Tumors can absorb sufficient nutrients and oxygen by

Reviews - The American Journal of Medicine

Mesodermal tumors: In 1930, Doege [I] de- scribed what may have been the first mesodermal lesion associated with hypoglycemia. The patient was a fifty year old white man in whom gener- alized malaise, cough, dyspnea and chest pain developed in September 1927. Physical and

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April 15th, 2012 - DOEGE1 Reported In 1930 The First Case Of Fibro Sarcoma Associated With Hypoglyccmia However It Was Not Until 1942 That The Specific Syndrome Of Spontaneous Hypoglycemia Associated With Tumors Of Mesodermal Origin Was Clearly Recognized 2 Since That Time 39 New Cases Have Been Described 3 The Location Of The

BRIEF REVIEWS - Cell

Hypoglycemia associated with nonislet cell tumors, also called nonislet cell tumor hypoglycemia (NICTH) or extra- pancreatic tumor hypoglycemia (EPTH), has puzzled endocrinologists for many years [for a review, see Unger (1966) and Kahn (1980)]. Hypoglycemia in tumor patients is a fasting hypoglycemia. The tumors are mostly of mesodermal or

1962 ANNUAL MEETING PROGRAM

chiefly large extrapulmonary growths of certain mesodermal types The tumor may be present for some years before the metabolic disturbances become manifest. If treatment is unduly delay ed, chronic hypoglycemia may result in brain damage. With surgical excision of these tumors a return of the blood sugar to normal levels can usually be anticipated.

Vascular Growth Factors and Lymphangiogenesis

C. Vascular tumors express VEGFR-3 in the endothelium 687 V. Tumorigenesis and Metastasis 688 A. Lymphatic vasculature and growth factors in tumors 688 B. Mechanisms of blood vascular and lymphatic metastasis 689 C. VEGF-C, VEGF-D, and tumor metastases 689 VI. Implications for the Human Disease Therapy 692 A. Antiangiogenic and antimetastatic

Large Fibrogenic Tumors and Hypoglycemia

from symptoms of hypoglycemia. HYPOGLYCEMIA associated with large fibro-genic extrapancreatic neoplasms has been cited, to our knowledge, only 25 times in medical literature. The tumors in this group have been of mesothelial origin, and in varying stages of cellular maturity. The mechanism by which such tumors influence carbohydrate metabolism

Hemangiopericytoma Associated with Hypoglycemia*

plasms associated with hypoglycemia are being reported with increasing frequency. In 1961 Lowbeer [ 71 recorded twenty-five tumors of mesodermal origin and twenty-three of epithelial origin. In Odell s recent review [Z] sixty-four mesenchymal, twenty-seven epithelial (twenty-one hepatic and six adrenal carcinomas)

ASSOCIACIO D ' NATOMIA PATOLOGICA HEMANGIOPERICITOMA PULMONAR

ASSOCIACIO D ' NATOMIA PATOLOGICA HEMANGIOPERICITOMA PULMONAR. OBSERVAC IO N DE UN CASO P. ABLANEDO, M. FRESNO, J. c. LORENZO INTRODUCC IÓN.-E l hemangiopericitoma es u n tumor vascular re­

Large Retroperitoneal Leiomyosarcoma

plastic hypoglycemia, which is usually secondary to tumor production of insulin-like growth factor 2.4 Clinically, leiomyosarcomas differ from liposarcoma by their tendency to metastasize either to the lung or to the liver with the lung being a more frequent site for metasta-sis. This may be diagnosed at the time of presentation and

7 Management of Abdominopelvic Sarcoma

subtle because these tumors may progress for long time periods without causing overt symptoms.1 Further confusion may arise when abdominal and pelvic sarcomas mimic the more common types of gastroin-testinal malignancy. However, complete cancer resection of even large abdominal and pelvic sarcomas can be associated with long-term survival and

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April 15th, 2012 - DOEGE1 reported in 1930 the first case of fibro sarcoma associated with hypoglyccmia however it was not until 1942 that the specific syndrome of spontaneous hypoglycemia associated with tumors of mesodermal origin was clearly recognized 2 Since that time 39 new cases have been described 3 The location of the tumors has been

Title Table of Contents (Acta Urologica Japonica Vol.38, No.6

Adrenal Myelolipoma Associated with Cushing's Syndrome: A Case of Retrovesical Fibrosarcoma with Severe Hypoglycemia Malignant Mesodermal Mixed Tumor of the

Bioassay Of Oxytocin - talkboutnet.ftik.usm.ac.id

april 15th, 2012 - doege1 reported in 1930 the first case of fibro sarcoma associated with hypoglyccmia however it was not until 1942 that the specific syndrome of spontaneous hypoglycemia associated with tumors of mesodermal origin was clearly recognized 2 since that time 39 new cases have been described 3 the location of the

CASE SERIES OF MEDIASTINAL MASSES A SINGLE INSTITUTIONAL

children, neurogenic tumors are the most common, followed by lymphomas, foregut cysts, and benign germ cell tumors. In adults, thymic tumors are the most common surgically treated mediastinal tumors. Treatment strategies for mediastinal tumors and cysts are quite broad, depending on the nature of the disease(1).

Cancer Prone Disease Section

associated with hemihypertrophy. Phenotype and clinics Multiple features that occur variably; most prominent is the EMG triad (exomphalos-macroglossia-gigantism): apart from the abdominal wall defects and pre- and postnatal growth abnormalities, earlobe pits or creases, facial nevus flammeus, hypoglycemia, renal

VETD 12 3con3.1 2

coma (malignant mixed muellerian (mesodermal) tumor) of the female genital tract: immunohistochemical and ultrastructural analysis of 28 cases. Hum Pathol 24:132 142. 3. Geisinger KR, Dabbs DJ, Marshall RB: 1987, Malignant mixed muellerian tumors: an ultrastructural and immunohistochemical analysis with histogenesis considerations. Cancer 59

HYPOGLYCEMIA ASSOCIATED WITH EXTRAPAN CREATIC TUMORS An

1929.79 l7 Most of the tumors have been of mesodermal origin, but a few cases of hy- poglycemia have been associated with epi- thelial tumors, notably carcinoma of the liver, gastrointestinal tract, and adrenal glands.40 l1. 29 The pathogenesis of the hypoglycemia has been a point of much conjecture, and

FRANK J. VEITH - CURRICULUM VITAE

Crocker DW, Veith FJ: Mesodermal tumors associated with hypoglycemia. Ann Surg, 161:418, 1965. Veith FJ, Luck RJ, Murray JE: The effects of splenectomy on immunosuppressive regimens in dog and man. Surg Gynecol Obstet, 121:299, 1965. Brooks JR, Veith FJ: The timing and choice of surgery for ulcerative colitis. JAMA, 194:115, 1965.