Kinetic Analysis Of Hybridoma Growth And Monoclonal Antibody Production In Semicontinuous Culture

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Semicontinuous cultures as a tool for characterization of

#Corresponding author Semicontinuous cultures as a tool for characterization of murine hybridoma 1E10 cells #Svieta Victores, Adolfo Castillo, Evelyn Faife, Yamilet Rabasa, Yaretnis Rodríguez,

Luis E Rojas, Julio Palacios, Alvio Figueredo

were equivalent to those expected for a continuous culture, the semicontinuous operation mode being a much simpler variant. Up to now there are only scarce reports on using semicontinuous cultures as a feasible alternative to simulate the kinetic behavior at stationary states. Finally, the antibody production pattern was confirmed as growth