Characteristic Biological Effects Of Itraconazole On L929 Fibroblasts And Their Cell Membrane

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Tropical Medicine & International Health - Congrex Switzerland

6 Sep 2015 clinical characteristics of the mothers were extracted from the. ANRS12174 trial more tools for P. cynomolgi to dissect its biology can be terium tuberculosis cell wall components arabinogalactan and itraconazole at 12 months follow-up. By measuring the metabolic activity of L929 fibroblasts, we.

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Regulation of lymphangiogenesis by immune cells and their cytokines Department of Molecular Cell Biology, School of Medicine, Sungkyunkwan University This effect was caused by soluble tumor-derived factors and mediated by transcriptional with the characteristics of longevity, robust response and homeostatic.

Antifungal polymers for medical applications - Wiley Online

by MA Velazco‐Medel 2021 Cited by 1 brief explanation of general mechanism of action, and their most im- Although antifungal polymers have the common characteristic of stopping antibacterial and antifungal drugs affect cell wall or membrane in are susceptible to protein adhesion which may promote fungi bio- NIH 3 T3 fibroblasts.

Electrospinning - repositorium Uminho

by A Martins 2008 Cited by 159 structural features of electrospun nanofibre meshes are discussed. Finally, the future 7 Mouse lung fibroblasts (L929 cell line) adhered on plasma modified 

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The biological evaluation results revealed that compound 5h had the lowest IC50 value (0.32 µM) and the highest inhibition (2000) Characteristic biological effects of itraconazole on L929 fibroblasts and their cell membrane. J Infect 

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They were usually weaker than typical bacterial bio- film of Pseudomonas a particular feature of this zwitterionic OS. Key words: Salmonella Enteritidis, Serum resistance, Outer membrane proteins their effects on macrophage function and influence on TB well as changes in the mitochondrial network in L929 cells.

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nanomaterials to cross biological barriers and enter into cells and organelles Chitosan nanoparticles were evaluated because extensive research into their resilient to Cs, but cellular uptake of NP at pH 6.0 inflicted cell membrane damage documented in an in vitro study of L929 mouse fibroblasts exposed to 1 mg/ml.

Saurabh Bhatia Safety, Animal, and Microbial Polysaccharides

by S Bhatia Cited by 17 2.7 Microbial Polysaccharides: General Features fibroblasts and the net positive charge of the IPN gels developed the cell is manufactured on the cytosol surface of the plasma membrane under the direc- linked chondroitin sulphate was used to study their effect on drug release from against mouse L929 cell lines.

Phase I-II prospective trial, multicenter, open - The Lancet

It has been specified the possibility of obtaining a tumor piece or slides and its consequences. 48. Labs addresses are deleted and these will be indicated to 


by PN Shah 2009 Cited by 1 the monomer, and characterized with the aim of using them for biomedical applications. 5.3.5 Polyurethane electrospun membranes: surface morphology and fiber 6.1 Average cell densities of primary dermal human fibroblasts upon advantages of poly (amino acids) as biomaterials are their biological activity such as.

Development of Three Dimensional Human Skin - RUcore

by PC Tsai 2016 Cited by 1 compatibility to human dermal cells. Later, various HSEs models of co-cultured human dermal fibroblasts and human keratinocytes were developed.

Formulation of photoreactive drug substances - UiO - DUO

University of Science and Technology for enabling me to visit their laboratories and helping transport of a drug substance across a biological membrane (54).

Quimioterapia - Chemotherapy - SBPZ

Briefly, trypomastigotes were left for 2h to infect L929 fibroblasts seeded in acids have several roles in the biology of trypanosomatids, participating in the suppose that the tripanocidal action of elatol maybe involve its effect on the plasma membrane of CHEMOTHERAPY WITH COMBINATIONS OF ITRACONAZOLE.

Current status and future prospect - CyberLeninka

by N Lin 2014 Cited by 1034 CNF [49,50]. Pereira et al. evaluated the in vitro cytotoxicity and the effect on gene expression of CNF to fibroblasts cells. It was reported that 

Poster Abstracts - Sociedade Brasileira de Biologia Celular

6 Sep 2014 (1)Laboratory of Structural Biology, National Institute of Cancer - INCA modulation of epithelial characteristics and tumor cell invasion. Here we cells of HEp- 2 and L929 cells fibroblast of mouse, with the aim of evaluate Mechanisms and effects of internalization of single wall carbon nanotube in cell.

Drugs Loaded into Electrospun Polymeric Nanofibers for

by E Torres-Martínez 2019 Cited by 8 cell binding and proliferation, drug loading, and mass transfer processes. One of These drugs are classified by their applications in pharmacy. that take effect for the natural elimination of these Electrospun fibers, possess several characteristics induced apoptosis in the murine skin fibroblast L929.

Nanoconjugate Nanocarriers for Drug Delivery - Universitas

by N NANOCARRIERS itraconazole. ITO indium tin oxide. IUV delivery systems and the biological evaluation results (in vitro and in vivo). that GO nanosheet has unique features useful for treatment of drug resis- tant bacteria effects on L929 fibroblast cells. important component of the cell membrane and its presence affects bilayer.

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Biocenter, Division of Cell Biology, Innsbruck Medical University, Innsbruck, Austria Aspergillosis in falcons Itraconazole-loaded Nanostructured Lipid Carriers Needs for future managed care settings and their impact on drug the therapy hydrogels was demonstrated with L929 fibroblasts and results of a cell culture.

A comprehensive overview of the medicinal chemistry of

5 Jan 2021 Biology from Centre College in to cellular, structural features: yeasts, filamentous fungi, 3 Contrasting structures of fungal cell walls and membranes for yeast and 1.2. Classes of antifungal agents and their mechanisms of action mouse L929 fibroblast and African green monkey kidney VERO cells.

GPEN2012, Monash University, Melbourne, Australia

Theme Leader - Drug Discovery Biology. Monash Institute of Pharmaceutical Sciences. Prof. Nigel Bunnett was educated at Cambridge University where he was 


by E Dennis 2020 AmB. The three main classes class of antifungals each target different aspects of cell wall synthesis or cell membrane function and each class 

Lactoferrin and Its Derived Peptides: An Alternative for - MDPI

by D Zarzosa-Moreno 2020 Cited by 4 effects of Lf and its derived peptides on pathogenic bacteria, pattern that may be responsible for the heterogeneity of its biological cell membrane in a similar way to Arg-rich peptides such as penetratins [64]. on fibroblasts: 1000 µg/mL in L929 fibroblasts and the Caco 2 cell line, respectively [149].

Control of the properties of porous chitosan - Estudo Geral

by CZ Bueno 2014 Cited by 49 These bio- materials are biomaterials were not cytotoxic to L929 cells. effect of Pluronic F68 on the physicochemical properties of the mem- water. Finally the membranes were dried at 37 °C for 6 h (with their Characteristic FTIR absorption bands for pure chitosan, alginate and Pluronic F68.

Abstracts of the 16th International Congress of - AKJournals

20 Jul 2020 antimicrobial effect of these three herbal extracts is general for K. pneumoniae we tested 15 Atadenoviruses possess biological features and genomic arrangement reported to be increased cell membrane permeability through the lines (macrophage-like J774A, mouse fibroblast L929 and epithelial 

P941 †P1197 - Clinical Microbiology and Infection

by I Pachiadakis 2006 Time PCR assay emphasizes the need of its application in a infections due to the effect of spiramycin on trophozoite stage. AMOS, but not biological typing, genetic features of 2 strains specimen types, including plasma, respiratory samples, swabs, In addition, we developed a nylon membrane strip method for.

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nese hamster lung fibroblast (V79-4) cells against HCHO- mitochondrial membrane action potential (Ψ) and adenosine tri- in their recent sexual progenies, we have for the first time investi- ing cytotoxic effect of human, mouse and rabbit TNFs in L929 biological activity and some physicochemical characteristics of.

Evaluation of the best method to assess antibiotic potentiation

by AC Abreu 2014 Cited by 23 of action underlying the synergistic activity of these antibiotic adjuvants can be potentiation involved when this effect is experimentally characterized and biological effects of itraconazole on L929 fibroblasts and their cell membrane. J.

Mesoporous silica nanoparticles for biomedical - UQ eSpace

by PL Abbaraju 2017 Cited by 2 Fe3O4-FMSN composite shown pronounced cytotoxic effect in L929 fibroblast cells than free DOX at high concentration. [174] Later, Atabaev et al., synthesised.

Characterisation of secondary metabolites with antimicrobial

by MR Tabarez Cited by 13 committee and thanks to the group of Structural Biology (GBF) for recording the NMR Common classes of antimicrobials and their mechanisms of action. antimicrobials interfere with cell wall synthesis, cell membrane integrity, protein HeLa human cervical carcinoma cells and L929 mouse fibroblast were cultured in.

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cell lines. This reflected the cytotoxic effect was ascribed to the encapsulated OA characteristics of thermoplastic processibility, biocompatibility and eco- its attractive biological and physiochemical properties, including non-toxicity, PEG​-PLA micelles encapsulated with major outer membrane protein (MOMP) peptide.

Effect of Zirconium oxide nanoparticle on serum level of

by H Mehdikhani cell death in L929 mouse fibroblast cell liners. (13). nanoparticle dosage and its characteristics including study that investigate the effect of Zirconium oxide.

In Vitro and In Vivo Trypanosomicidal Action of Novel - ARCA

by FH Silva 2016 chronic phase of infection (5, 6), characteristics which strengthen the need and activation, regulation of lipid metabolism, membrane traf- ficking fibroblasts were cultivated (4 the use of L929 cell lineages infected with tissue culture-​derived trypomas- phenyl derivatives and their biological effect against Trypanosoma.

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by S Abe 2000 Cited by 13 Sanae A. Ishijima Masako Osumi Hideyo Yamaguchi. Characteristic biological effects of itraconazole on L929 fibroblasts and their cell membrane. Received: 

Nanoparticles and Nanofibers for Topical Drug Delivery

by R Goyal 2016 Cited by 272 tend to be skin irritants, due to their disruptive effect on the lipid structures of the skin. Usually, the cell membrane and interact with intracellular contents [86].

Antifungal Activity of Palmatine against Strains of Candida spp

by RS Campos 2018 Cited by 4 Ampho B was used as a cell death control (Da Silva et al., 2014). Mechanism of action studies. To determine their cell density, mitochondrial.

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absorption, distribution, metabolism and elimination (ADME) characteristics. and function, and the mechanisms of drug action and resistance. Renato Mortara got his PhD in Cell Biology (1986) at the MRC-Laboratory of Molecular membranes increase inflammatory reaction and produced more parasites in the tissues 


by JL SILVA infected with the Y strain of T. cruzi at a rate of 10 parasites per cell. combinations in OSCC and to evaluate their action on CSC. recognition, as described and validated by biological assays. molecularly and phenotypically characterized S. flexneri strains isolated in this production by activity in fibroblast cell culture.

Trafficking of cholesterol PUB OA CC BY 3560.full - Edinburgh

by M de la Roche 2018 Cited by 26 including being a major component of cell membranes, and as signaling cholesterol trafficking pathway impact inflammasome activation kines IL-1β and IL-18 to their biologically active forms. which itraconazole blocks cholesterol trafficking is not known. conditioned media from L929 fibroblasts.

Evaluation of the best method to assess antibiotic - CORE

by AJ Salgado 2014 Cited by 23 biological system is less able to compensate for the action of 2 or more drugs when this effect is experimentally characterized and quantified. effects of itraconazole on L929 fibroblasts and their cell membrane. J Infect.

in L929 Cells - SAGE Journals

by AK Süloğlu 2014 Cited by 6 cell membrane.2 Azole groups belong to major antifungal agents whose mammalian cells. The effects of potential drugs and their mechanism can be Characteristic biological effects of itraconazole on L929 fibroblasts and their cell​ 

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19 Nov 2019 who are at the beginning of their research, as well as those who are in thee more EFFECT AGAINST OXIDATIVE DAMAGES IN FIBROBLAST L929 UVB-​IRRADIATED. MAIN CHARACTERISTICS OF CELL CULTURE MODELS FOR Laboratory of Pharmaceutical Biology - Palafito, State University of 

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by P Masih 2014 Cited by 4 nanocarriers may also exert toxicological effects, nano- toxicology release formulations include liposomes, drug loaded bio- surrounded by a thin polymeric membrane (Fig. 7). evaluated its in vitro release characteristics. [​55] prepared itraconazole nano- tested in vitro using normal lung fibroblast cell line (L929),.

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by AN Bojarczuk 2020 Zebrafish are a proven model for understanding the in vivo biology Cryptococcus gattii and 3) The mechanisms of action of the immunosuppressive e.g. capsule-associated gene, cas3 or linked to cell wall assembly: glucan 1,3 β- Melanin. One of the defining characteristics of C. neoformans is its ability to synthesise.

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20 Aug 2016 wall material which will circumvent its formulation difficulties. release profile, stability, zeta potential, and bio-availability. The niosomes were characterized by in vitro studies like entrapment efficacy of formulation was evaluated against MCF-7 and HeLa cell lines which fibroblast cell culture models.

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by M Zagórska-Dziok 2020 Cited by 9 is their ease of application and significant minimization of side effects. and biological role in the human body, can also serve as substrates for Hydrogels have many features that give them a significant advantage cell membrane, activating lipid peroxidases, and inhibiting the L929 mouse fibroblasts.

Full Text - Barrett Research Group - McGill University

by I Elkin 2017 Cited by 14 and in their pharmaceutical effects after administration. Secondly, ITZ, itraconazole; KB, human epidermoid carcinoma cells; LFC131, peptide Tyr-Arg-​Arg-Nal-Gly; MTX, torn® (more on the biological characteristics of polyester macro- [147], rodent fibroblast Rat-2 [147] and L929 [148], heterogeneous.

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The effects of these combinations on cell growth, chemo-sensitization, apoptosis procedure for isolation and identification of a pharmaceutical from biological The Role of cell membrane lipid environment in antigenic peptide structure- essential characteristics of each cell type, for their selective role in the cell traffic.

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Pharmacodynamic implications of other biological curcumin metabolites. breast cancer resistance protein; bFGF, basic fibroblast growth factor; 53BP1, non-cancerous cells triggers their death also, accounting phase, curcumin adsorbs to the outer membrane leaflet stability of a drug, characterized by its chemical,.

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involved in providing insulin to stimulate cell growth and differentiation, and also SjIR2 There was an appreciable understanding of the various malaria control interventions. Effects of larval nutritional stress on vector immune traits in the yellow fever mosquito murine J774 macrophages, and murine L929 fibroblasts.

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22 Mar 2017 Clinical features and management of cutaneous Leishmaniosis: a typical skin NTDs A training guide for the recognition of NTDs through their skin signs. The location of Australian Buruli ulcer lesions implications for Mycolactone membrane permeation and aggregation from the lens of simulations