Mutant P53 And Aberrant Cytosine Methylation Cooperate To Silence Gene Expression
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Epigenetic Dysregulation in Thyroid Neoplasia
Epigenetic gene regulation Epigenetic modiﬁcation is responsible for regulation of gene expression by mammalian cells without involving changes in the underlying genomic DNA sequence (Fig. 1). The mechanisms include methylation of cytosine * Corresponding author. Ontario Cancer Institute, 610 University Avenue #8-327, Toronto, ON, M5P 2S3